Prognostic significance of differential expression of angiogenic genes in women with high-grade serous ovarian carcinoma

Abstract Objectives To identify angiogenic biomarkers associated with tumor angiogenesis and clinical outcome in high-grade serous ovarian cancer (HGSC). Methods 51 HGSC samples were analyzed using Affymetrix HG-U133A microarray. Microvessel density (MVD) counts were determined using CD31 and CD105....

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Veröffentlicht in:	Gynecologic oncology 2015-10, Vol.139 (1), p.23-29
Hauptverfasser:	Siamakpour-Reihani, Sharareh, Owzar, Kouros, Jiang, Chen, Turner, Taylor, Deng, Yiwen, Bean, Sarah M, Horton, Janet K, Berchuck, Andrew, Marks, Jeffrey R, Dewhirst, Mark W, Alvarez Secord, Angeles
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Angiogenesis Antigens, CD - analysis Biomarkers Biomarkers, Tumor - genetics Cystadenocarcinoma, Serous - blood supply Cystadenocarcinoma, Serous - genetics Cystadenocarcinoma, Serous - pathology Endoglin Female Gene Expression Hematology, Oncology and Palliative Medicine High-grade serous ovarian carcinoma Humans Immunohistochemistry Middle Aged Neoplasm Grading Neovascularization, Pathologic - genetics Obstetrics and Gynecology Oligonucleotide Array Sequence Analysis Ovarian Neoplasms - blood supply Ovarian Neoplasms - genetics Ovarian Neoplasms - pathology Overall survival Platelet Endothelial Cell Adhesion Molecule-1 - analysis Prognosis Proportional Hazards Models Receptors, Cell Surface - analysis Survival Rate
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