mRNA encoding Sec61β, a tail-anchored protein, is localized on the endoplasmic reticulum

Although one pathway for the post-translational targeting of tail-anchored proteins to the endoplasmic reticulum (ER) has been well defined, it is unclear whether additional pathways exist. Here, we provide evidence that a subset of mRNAs encoding tail-anchored proteins, including Sec61β and nesprin...

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Veröffentlicht in:	Journal of cell science 2015-09, Vol.128 (18), p.3398-3410
Hauptverfasser:	Cui, Xianying A, Zhang, Hui, Ilan, Lena, Liu, Ai Xin, Kharchuk, Iryna, Palazzo, Alexander F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cercopithecus aethiops COS Cells Endoplasmic Reticulum - metabolism Humans Membrane Proteins - biosynthesis Microfilament Proteins - metabolism Nerve Tissue Proteins - metabolism Nuclear Proteins - metabolism Protein Transport Receptors, Cytoplasmic and Nuclear - metabolism RNA, Messenger - biosynthesis SEC Translocation Channels
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