Hippo signaling is required for Notch-dependent smooth muscle differentiation of neural crest

Notch signaling has well-defined roles in the assembly of arterial walls and in the development of the endothelium and smooth muscle of the vasculature. Hippo signaling regulates cellular growth in many tissues, and contributes to regulation of organ size, in addition to other functions. Here, we sh...

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Veröffentlicht in:	Development (Cambridge) 2015-09, Vol.142 (17), p.2962-2971
Hauptverfasser:	Manderfield, Lauren J, Aghajanian, Haig, Engleka, Kurt A, Lim, Lillian Y, Liu, Feiyan, Jain, Rajan, Li, Li, Olson, Eric N, Epstein, Jonathan A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - chemistry Adaptor Proteins, Signal Transducing - metabolism Animals Aorta, Thoracic - metabolism Cell Cycle Proteins Cell Differentiation DNA-Binding Proteins - metabolism Gene Deletion HEK293 Cells Humans Mesoderm - metabolism Mice Muscle, Smooth - metabolism Myocytes, Smooth Muscle - cytology Myocytes, Smooth Muscle - metabolism Neural Crest - cytology Phosphoproteins - chemistry Phosphoproteins - metabolism Protein Binding Protein Structure, Tertiary Protein-Serine-Threonine Kinases - metabolism Receptors, Notch - chemistry Receptors, Notch - metabolism Signal Transduction Transcription Factors - metabolism Transcription, Genetic
Online-Zugang:	Volltext
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