Hansenula polymorpha Hac1p Is Critical to Protein N-Glycosylation Activity Modulation, as Revealed by Functional and Transcriptomic Analyses

Aggregation of misfolded protein in the endoplasmic reticulum (ER) induces a cellular protective response to ER stress, the unfolded protein response (UPR), which is mediated by a basic leucine zipper (bZIP) transcription factor, Hac1p/Xbp1. In this study, we identified and studied the molecular fun...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Applied and Environmental Microbiology 2015-10, Vol.81 (20), p.6982-6993
Hauptverfasser:	Moon, Hye-Yun, Cheon, Seon Ah, Kim, Hyunah, Agaphonov, M O, Kwon, Ohsuk, Oh, Doo-Byoung, Kim, Jeong-Yoon, Kang, Hyun Ah
Format:	Artikel
Sprache:	eng
Schlagworte:	Basic-Leucine Zipper Transcription Factors - genetics Basic-Leucine Zipper Transcription Factors - metabolism Gene Deletion Gene expression Gene Expression Profiling Gene Expression Regulation, Fungal Genes Genetics and Molecular Biology Glycosylation Hansenula polymorpha Introns Molecular Sequence Data Pichia - genetics Pichia - growth & development Pichia - metabolism Pichia - radiation effects Protein Biosynthesis Proteins RNA, Messenger - genetics RNA, Messenger - metabolism Sequence Analysis, DNA Stress, Physiological Temperature Transcription factors Yeast
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!