Transcriptional Profiling of the Immune Response to Marburg Virus Infection

Marburg virus is a genetically simple RNA virus that causes a severe hemorrhagic fever in humans and nonhuman primates. The mechanism of pathogenesis of the infection is not well understood, but it is well accepted that pathogenesis is appreciably driven by a hyperactive immune response. To better u...

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Veröffentlicht in:	Journal of virology 2015-10, Vol.89 (19), p.9865-9874
Hauptverfasser:	Connor, John H, Yen, Judy, Caballero, Ignacio S, Garamszegi, Sara, Malhotra, Shikha, Lin, Kenny, Hensley, Lisa, Goff, Arthur J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers - metabolism Cytokines - immunology Gene Expression Profiling Gene Expression Regulation - immunology Immunity, Innate - genetics Leukocytes, Mononuclear - metabolism Macaca mulatta Marburg virus Marburg Virus Disease - immunology Marburg Virus Disease - physiopathology Marburgvirus - immunology Microarray Analysis Pathogenesis and Immunity Real-Time Polymerase Chain Reaction
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