High-Affinity H7 Head and Stalk Domain-Specific Antibody Responses to an Inactivated Influenza H7N7 Vaccine After Priming With Live Attenuated Influenza Vaccine

Recent studies have shown that live attenuated influenza vaccines (LAIVs) expressing avian influenza virus hemagglutinins (HAs) prime for strong protective antibody responses to an inactivated influenza vaccine (IIV) containing the HA. To better understand this priming effect, we compared H7 HA head...

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Veröffentlicht in:	The Journal of infectious diseases 2015-10, Vol.212 (8), p.1270-1278
Hauptverfasser:	Halliley, Jessica L., Khurana, Surender, Krammer, Florian, Fitzgerald, Theresa, Coyle, Elizabeth M., Chung, Ka Yan, Baker, Steven F., Yang, Hongmei, Martínez-Sobrido, Luis, Treanor, John J., Subbarao, Kanta, Golding, Hana, Topham, David J., Sangster, Mark Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Neutralizing - blood Antibodies, Viral - blood B-Lymphocytes - immunology Cohort Studies Hemagglutination Inhibition Tests Humans Influenza A Virus, H7N7 Subtype - immunology Influenza Vaccines - immunology Influenza, Human - immunology Influenza, Human - prevention & control Influenza, Human - virology Major and Brief Reports Neutralization Tests PATHOGENESIS AND HOST RESPONSE Vaccines, Attenuated - immunology Vaccines, Inactivated - immunology
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