Quantitative Assessment of Multiorgan Sequestration of Parasites in Fatal Pediatric Cerebral Malaria

Children in sub-Saharan Africa continue to acquire and die from cerebral malaria, despite efforts to control or eliminate the causative agent, Plasmodium falciparum. We present a quantitative histopathological assessment of the sequestration of parasitized erythrocytes in multiple organs obtained du...

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Veröffentlicht in:	The Journal of infectious diseases 2015-10, Vol.212 (8), p.1317-1321
Hauptverfasser:	Milner, Danny A., Lee, Jonathan J., Frantzreb, Charles, Whitten, Richard O., Kamiza, Steve, Carr, Richard A., Pradham, Alana, Factor, Rachel E., Playforth, Krupa, Liomba, George, Dzamalala, Charles, Seydel, Karl B., Molyneux, Malcolm E., Taylor, Terrie E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Autopsy Brain - parasitology Brain - pathology Case-Control Studies Child Erythrocytes - parasitology Gastrointestinal Tract - parasitology Gastrointestinal Tract - pathology Humans Major and Brief Reports Malaria, Cerebral - mortality Malaria, Cerebral - parasitology Malaria, Cerebral - pathology Malaria, Falciparum - mortality Malaria, Falciparum - parasitology Malaria, Falciparum - pathology Malawi - epidemiology Parasite Load - methods Parasitemia PARASITES Plasmodium falciparum - isolation & purification Prospective Studies Skin - parasitology Skin - pathology Spleen - parasitology Spleen - pathology
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