Robust Algorithm for Systematic Classification of Malaria Late Treatment Failures as Recrudescence or Reinfection Using Microsatellite Genotyping

Routine therapeutic efficacy monitoring to measure the response to antimalarial treatment is a cornerstone of malaria control. To correctly measure drug efficacy, therapeutic efficacy studies require genotyping parasites from late treatment failures to differentiate between recrudescent infections a...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2015-10, Vol.59 (10), p.6096-6100
Hauptverfasser:	Plucinski, Mateusz M, Morton, Lindsay, Bushman, Mary, Dimbu, Pedro Rafael, Udhayakumar, Venkatachalam
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Antimalarials Antimalarials - therapeutic use Epidemiology and Surveillance Genotype Humans Malaria Malaria - drug therapy Malaria - genetics Microsatellite Repeats Microsatellite Repeats - genetics Monte Carlo Method Treatment Outcome
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