Prenatal Allospecific NK Cell Tolerance Hinges on Instructive Allorecognition through the Activating Receptor during Development

Little is known about how the prenatal interaction between NK cells and alloantigens shapes the developing NK cell repertoire toward tolerance or immunity. Specifically, the effect on NK cell education arising from developmental corecognition of alloantigens by activating and inhibitory receptors wi...

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Veröffentlicht in:The Journal of immunology (1950) 2015-08, Vol.195 (4), p.1506-1516
Hauptverfasser: Alhajjat, Amir M, Strong, Beverly S, Lee, Amanda E, Turner, Lucas E, Wadhwani, Ram K, Ortaldo, John R, Heusel, Jonathan W, Shaaban, Aimen F
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Sprache:eng
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