Pathogenic mechanism of an autism-associated neuroligin mutation involves altered AMPA-receptor trafficking

Neuroligins are postsynaptic cell-adhesion molecules that bind to presynaptic neurexins. Although the general synaptic role of neuroligins is undisputed, their specific functions at a synapse remain unclear, even controversial. Moreover, many neuroligin gene mutations were associated with autism, bu...

Ausführliche Beschreibung