A nanoparticle formula for delivering siRNA or miRNAs to tumor cells in cell culture and in vivo

This protocol is for the preparation of hyaluronic acid–based nanoparticles that are coupled to a zinc(II)-dipicolylamine analog that binds to phosphate anions and can therefore deliver the RNA into cells. To improve RNA delivery, we present a protocol to produce an RNA carrier based on a Zn(II)-dip...

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