Progressive retinal structure abnormalities in multiple system atrophy

ABSTRACT Background Objective measures of disease progression that can be used as endpoints in clinical trials of MSA are necessary. We studied retinal thickness in patients with MSA and assessed changes over time to determine its usefulness as an imaging biomarker of disease progression. Methods Th...

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Veröffentlicht in:	Movement disorders 2015-12, Vol.30 (14), p.1944-1953
Hauptverfasser:	Mendoza-Santiesteban, Carlos E., Palma, Jose-Alberto, Martinez, Jose, Norcliffe-Kaufmann, Lucy, Hedges III, Thomas R., Kaufmann, Horacio
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Color Perception - physiology Cross-Sectional Studies Disease Progression Female ganglion cell complex Humans Male Middle Aged Movement disorders multiple system atrophy Multiple System Atrophy - pathology Multiple System Atrophy - physiopathology optical coherence tomography Parkinson disease Retina - pathology Retina - physiopathology retinal nerve fiber layer Tomography, Optical Coherence unified multiple system atrophy rating scale Visual Acuity - physiology
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