Mechanisms of amyloid formation revealed by solution NMR

Amyloid fibrils are proteinaceous elongated aggregates involved in more than fifty human diseases. Recent advances in electron microscopy and solid state NMR have allowed the characterization of fibril structures to different extents of refinement. However, structural details about the mechanism of...

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Veröffentlicht in:Progress in nuclear magnetic resonance spectroscopy 2015-08, Vol.88-89, p.86-104
Hauptverfasser: Karamanos, Theodoros K, Kalverda, Arnout P, Thompson, Gary S, Radford, Sheena E
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Sprache:eng
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