Effects of acotiamide on esophageal motor function and gastroesophageal reflux in healthy volunteers

The prevalence of gastroesophageal reflux disease (GERD) has been increasing worldwide, with proton pump inhibitor (PPI) administration the current mainstay therapy for affected individuals. However, PPI efficacy is insufficient especially for non-erosive reflux disease. Although it has been reporte...

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Veröffentlicht in:	BMC gastroenterology 2015-09, Vol.15 (1), p.117-117, Article 117
Hauptverfasser:	Ishimura, Norihisa, Mori, Mami, Mikami, Hironobu, Shimura, Shino, Uno, Goichi, Aimi, Masahito, Oshima, Naoki, Ishihara, Shunji, Kinoshita, Yoshikazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Benzamides - pharmacology Benzamides - therapeutic use Care and treatment Complications and side effects Cross-Over Studies Development and progression Dosage and administration Drug therapy Electric Impedance Esophageal pH Monitoring Esophageal Sphincter, Lower - drug effects Esophageal Sphincter, Lower - physiology Female Gastroesophageal reflux Gastroesophageal Reflux - drug therapy Gastrointestinal agents Gastrointestinal Agents - pharmacology Gastrointestinal Agents - therapeutic use Healthy Volunteers Humans Male Manometry Medical colleges Patient outcomes Peristalsis - drug effects Postprandial Period Thiazoles - pharmacology Thiazoles - therapeutic use Young Adult
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