Global Promoter Targeting of a Conserved Lysine Deacetylase for Transcriptional Shutoff during Quiescence Entry

Quiescence is a conserved cell-cycle state characterized by cell-cycle arrest, increased stress resistance, enhanced longevity, and decreased transcriptional, translational, and metabolic output. Although quiescence plays essential roles in cell survival and normal differentiation, the molecular mec...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular cell 2015-09, Vol.59 (5), p.732-743
Hauptverfasser:	McKnight, Jeffrey N., Boerma, Joseph W., Breeden, Linda L., Tsukiyama, Toshio
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Cycle - genetics cell cycle checkpoints cell viability chromatin Chromatin - genetics Chromatin - metabolism Gene Deletion genes Genes, Fungal Histone Deacetylases - genetics Histone Deacetylases - metabolism longevity lysine Models, Biological Promoter Regions, Genetic Repressor Proteins - genetics Repressor Proteins - metabolism Saccharomyces cerevisiae - cytology Saccharomyces cerevisiae - enzymology Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism stress tolerance Trans-Activators - metabolism transcription (genetics) transcription factors Transcription, Genetic Transcriptome translation (genetics)
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!