Geometric guidance of integrin mediated traction stress during stem cell differentiation

Abstract Cells sense and transduce the chemical and mechanical properties of their microenvironment through cell surface integrin receptors. Traction stress exerted by cells on the extracellular matrix mediates focal adhesion stabilization and regulation of the cytoskeleton for directing biological...

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Veröffentlicht in:	Biomaterials 2015-11, Vol.69, p.174-183
Hauptverfasser:	Lee, Junmin, Abdeen, Amr A, Tang, Xin, Saif, Taher A, Kilian, Kristopher A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylic Resins - chemistry Adhesion Advanced Basic Science Biocompatible Materials - chemistry Biomaterials Biomedical materials Cell Adhesion Cell Differentiation Cell Line Cell Shape Dentistry Differentiation Extracellular Matrix Proteins - chemistry Hardness Humans Hydrogels - chemistry Immobilized Proteins - chemistry Integrin Integrins - metabolism Mesenchymal stem cells Mesenchymal Stem Cells - cytology Mesenchymal Stem Cells - metabolism Microenvironment Stem cells Stress, Mechanical Stresses Surgical implants Tissue Array Analysis Traction Traction stress
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