Epsilon aminocaproic acid reduces blood transfusion and improves the coagulation test after pediatric open-heart surgery: a meta-analysis of 5 clinical trials

Excessive postoperative blood loss after cardiopulmonary bypass is a common problem, especially in patients suffering from congenital heart diseases. The efficacy of epsilon aminocaproic acid (EACA) as a prophylactic treatment for postoperative bleeding after pediatric open-heart surgery has not bee...

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Veröffentlicht in:	International journal of clinical and experimental pathology 2015-01, Vol.8 (7), p.7978-7987
Hauptverfasser:	Lu, Jun, Meng, Haoyu, Meng, Zhaoyi, Sun, Ying, Pribis, John P, Zhu, Chunyan, Li, Quan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Age Factors Aminocaproic Acid - adverse effects Aminocaproic Acid - therapeutic use Antifibrinolytic Agents - adverse effects Antifibrinolytic Agents - therapeutic use Blood Coagulation - drug effects Blood Coagulation Tests Blood Transfusion Cardiac Surgical Procedures - adverse effects Chi-Square Distribution Child Child, Preschool Heart Defects, Congenital - surgery Humans Infant Odds Ratio Original Postoperative Hemorrhage - blood Postoperative Hemorrhage - diagnosis Postoperative Hemorrhage - prevention & control Predictive Value of Tests Randomized Controlled Trials as Topic Risk Factors Time Factors Treatment Outcome
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