Susceptibility loci in lung cancer and COPD: association of IREB2 and FAM13A with pulmonary diseases

Genome-wide association studies have identified loci at 15q25 ( IREB2 ) and 4q22 ( FAM13A ), associated with lung cancer (LC) and chronic obstructive pulmonary disease (COPD). The aim of our research was to determine the association of IREB2 and FAM13A SNPs with LC and severe/very severe COPD patien...

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Veröffentlicht in:	Scientific reports 2015-08, Vol.5 (1), p.13502-13502, Article 13502
Hauptverfasser:	Ziółkowska-Suchanek, Iwona, Mosor, Maria, Gabryel, Piotr, Grabicki, Marcin, Żurawek, Magdalena, Fichna, Marta, Strauss, Ewa, Batura-Gabryel, Halina, Dyszkiewicz, Wojciech, Nowak, Jerzy
Format:	Artikel
Sprache:	eng
Schlagworte:	631/208/205 692/53/2422 Alleles Case-Control Studies Chromosome 15 Chronic obstructive pulmonary disease Female Gene Frequency Genetic Association Studies Genetic Loci Genetic Predisposition to Disease Genome-wide association studies Genomes GTPase-Activating Proteins - genetics Haplotypes Haplotypes - genetics Health risk assessment Humanities and Social Sciences Humans Iron Regulatory Protein 2 - genetics Linkage Disequilibrium - genetics Logistic Models Lung cancer Lung diseases Lung Neoplasms - genetics Male Middle Aged multidisciplinary Obstructive lung disease Polymorphism, Single Nucleotide - genetics Pulmonary Disease, Chronic Obstructive - genetics Risk Factors Science Single-nucleotide polymorphism Smoking
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