Complex contributions of fibronectin to initiation and maturation of microfibrils

Fibrillins constitute the backbone of extracellular multifunctional assemblies present in elastic and non-elastic matrices, termed microfibrils. Assembly of fibrillins into microfibrils and their homoeostasis is poorly understood and is often compromised in connective tissue disorders such as Marfan...

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Veröffentlicht in:	Biochemical journal 2013-12, Vol.456 (2), p.283-295
Hauptverfasser:	Sabatier, Laetitia, Djokic, Jelena, Fagotto-Kaufmann, Christine, Chen, Marian, Annis, Douglas S, Mosher, Deane F, Reinhardt, Dieter P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesins, Bacterial - chemistry Adolescent Binding Sites Binding, Competitive Cells, Cultured Child Child, Preschool Fibrillin-1 Fibrillins Fibronectins - chemistry Fibronectins - metabolism Homeostasis Humans Infant Microfibrils - metabolism Microfilament Proteins - chemistry Microfilament Proteins - metabolism Protein Interaction Domains and Motifs Protein Interaction Mapping Protein Multimerization Protein Transport
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