Factors determining biochemical recurrence in low-risk prostate cancer patients who underwent radical prostatectomy

Factors determining biochemical recurrence in low-risk prostate cancer patients who underwent radical prostatectomy

This study was conducted to research the factors determining biochemical recurrence (BCR) in low-risk localized prostate cancer patients who underwent radical prostatectomy (RP). We retrospectively analyzed the data of 504 patients who had undergone RP between 2003 and 2013 at our clinic. One hundre...

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Veröffentlicht in:Turkish journal of urology 2015-06, Vol.41 (2), p.61-66
Hauptverfasser: Ün, Sıtkı, Türk, Hakan, Koca, Osman, Divrik, Rauf Taner, Zorlu, Ferruh
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Urooncology
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container_end_page 66
container_issue 2
container_start_page 61
container_title Turkish journal of urology
container_volume 41
creator Ün, Sıtkı
Türk, Hakan
Koca, Osman
Divrik, Rauf Taner
Zorlu, Ferruh
description This study was conducted to research the factors determining biochemical recurrence (BCR) in low-risk localized prostate cancer patients who underwent radical prostatectomy (RP). We retrospectively analyzed the data of 504 patients who had undergone RP between 2003 and 2013 at our clinic. One hundred and fifty-two patients who underwent RP for low-risk prostate cancer were included in the study. The mean follow-up period for patients was 58.7 (21-229) months. The mean age of the patients was 63.7±7.2 years (49-79). The mean prostate specific antigen (PSA) value was 5.25±4.22 ng/mL (3.58-9.45). The BCR rate after the operation was 25% (38/152). In the univariate analysis, recurrence determining factors were shown to include extracapsular involvement (ECI) (p=0.004), capsular invasion (CI) (p=0.001), age (p=0.014), and tumor size (p=0.006). However, only CI was found to be significant in multivariate analysis (p=0.001). Capsular invasion is an independent risk factor in low-risk prostate cancer patients who underwent RP for BCR.
doi_str_mv 10.5152/tud.2015.65624
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title Factors determining biochemical recurrence in low-risk prostate cancer patients who underwent radical prostatectomy
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