Effect of Alendronate on Bone Formation during Tooth Extraction Wound Healing

Alendronate (ALN) is an antiresorptive agent widely used for the treatment of osteoporosis. Its suppressive effect on osteoclasts has been extensively studied. However, the effect of ALN on bone formation is not as clear as its effect on resorption. The objective was to determine the effect of short...

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Veröffentlicht in:	Journal of dental research 2015-09, Vol.94 (9), p.1251-1258
Hauptverfasser:	Tanoue, R., Koi, K., Yamashita, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alendronate - pharmacology Alendronic acid Alkaline phosphatase Alkaline Phosphatase - metabolism Animals Bisphosphonates Blood vessels Bone Development - drug effects Bone growth Bone healing Bone mass Bone morphogenetic protein 2 Bone Morphogenetic Proteins - metabolism Dentistry Gene expression Inflammation Leukocytes (neutrophilic) Menopause Mice Mice, Inbred C57BL Neutrophils Osteoclasts Osteogenesis Osteoporosis Parathyroid Parathyroid hormone Phosphatase Research Reports Retention Ribonucleic acid RNA Root resorption Short term Signal Transduction Teeth Tooth Extraction Tooth extractions Trauma Vertebrae Wound Healing
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