Intermittent high dose proton pump inhibitor enhances the antitumor effects of chemotherapy in metastatic breast cancer

Acidity is a hallmark of malignant tumor, representing a very efficient mechanism of chemoresistance. Proton pump inhibitors (PPI) at high dosage have been shown to sensitize chemoresistant human tumor cells and tumors to cytotoxic molecules. The aim of this pilot study was to investigate the effica...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of experimental & clinical cancer research 2015-08, Vol.34 (1), p.85, Article 85
Hauptverfasser:	Wang, Bi-Yun, Zhang, Jian, Wang, Jia-Lei, Sun, Si, Wang, Zhong-Hua, Wang, Lei-Ping, Zhang, Qun-Ling, Lv, Fang-Fang, Cao, En-Ying, Shao, Zhi-Min, Fais, Stefano, Hu, Xi-Chun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic Combined Chemotherapy Protocols - therapeutic use Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - mortality Breast Neoplasms - pathology Cancer Care and treatment Chemotherapy Complications and side effects Dosage and administration Drug Administration Schedule Esomeprazole - administration & dosage Female Health aspects Humans Lung Neoplasms - drug therapy Lung Neoplasms - mortality Lung Neoplasms - secondary Metastasis Middle Aged Pilot Projects Proton pump inhibitors Proton Pump Inhibitors - administration & dosage Risk factors Treatment Outcome
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!