Identification of the minimal binding region of a Plasmodium falciparum IgM binding PfEMP1 domain

[Display omitted] •Many pathogens bind the Fc region of host immunoglobulin to evade immunity.•We examined a Plasmodium falciparum IgM binding PfEMP1 domain TM284var1 DBL4ζ.•We identified the minimal IgM binding region comprising subdomain 2 and flanking regions.•Specific charged amino acids were mu...

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