Current Methods for Automated Filtering of Multiple Sequence Alignments Frequently Worsen Single-Gene Phylogenetic Inference

Phylogenetic inference is generally performed on the basis of multiple sequence alignments (MSA). Because errors in an alignment can lead to errors in tree estimation, there is a strong interest in identifying and removing unreliable parts of the alignment. In recent years several automated filterin...

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Veröffentlicht in:	Systematic biology 2015-09, Vol.64 (5), p.778-791
Hauptverfasser:	Tan, Ge, Muffato, Matthieu, Ledergerber, Christian, Herrero, Javier, Goldman, Nick, Gil, Manuel, Dessimoz, Christophe
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Classification - methods Comparative analysis Genome - genetics Genomes Phylogenetics Phylogeny Regular Reproducibility of Results Sequence Alignment Simulation
Online-Zugang:	Volltext
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