Pharmacodynamics of fosfomycin: insights into clinical use for antimicrobial resistance

The aim of this study was to improve the understanding of the pharmacokinetic-pharmacodynamic relationships of fosfomycin against extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli strains that have different fosfomycin MICs. Our methods included the use of a hollow fiber infection m...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2015-09, Vol.59 (9), p.5602-5610
Hauptverfasser:	Docobo-Pérez, F, Drusano, G L, Johnson, A, Goodwin, J, Whalley, S, Ramos-Martín, V, Ballestero-Tellez, M, Rodriguez-Martinez, J M, Conejo, M C, van Guilder, M, Rodríguez-Baño, J, Pascual, A, Hope, W W
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Anti-Infective Agents Anti-Infective Agents - pharmacology Drug Resistance, Multiple, Bacterial - genetics Escherichia coli Escherichia coli - drug effects Fosfomycin Fosfomycin - pharmacokinetics Fosfomycin - pharmacology Meropenem Microbial Sensitivity Tests Mutation Pharmacology Thienamycins - pharmacokinetics Thienamycins - pharmacology
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