Analysis of cardiovascular responses to the H2S donors Na2S and NaHS in the rat

Hydrogen sulfide (H2S) is an endogenous gaseous molecule formed from L-cysteine in vascular tissue. In the present study, cardiovascular responses to the H2S donors Na2S and NaHS were investigated in the anesthetized rat. The intravenous injections of Na2S and NaHS 0.03-0.5 mg/kg produced dose-relat...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2015-08, Vol.309 (4), p.H605-H614
Hauptverfasser:	Yoo, Daniel, Jupiter, Ryan C, Pankey, Edward A, Reddy, Vishwaradh G, Edward, Justin A, Swan, Kevin W, Peak, Taylor C, Mostany, Ricardo, Kadowitz, Philip J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arachidonic Acid - metabolism Blood Pressure - drug effects Cardiac Output - drug effects Cyclic GMP - metabolism Heart Rate - drug effects Hydrogen Sulfide - pharmacology Male Nitric Oxide - metabolism Potassium Channels - metabolism Rats Rats, Sprague-Dawley Sulfides - pharmacology Vascular Biology and Microcirculation Vascular Resistance - drug effects
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