The Omega-3 Fatty Acid Docosahexaenoic Acid Modulates Inflammatory Mediator Release in Human Alveolar Cells Exposed to Bronchoalveolar Lavage Fluid of ARDS Patients

Background. This study investigated whether the 1 : 2 ω-3/ω-6 ratio may reduce proinflammatory response in human alveolar cells (A549) exposed to an ex vivo inflammatory stimulus (bronchoalveolar lavage fluid (BALF) of acute respiratory distress syndrome (ARDS) patients). Methods. We exposed A549 ce...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	BioMed research international 2015-01, Vol.2015 (2015), p.1-11
Hauptverfasser:	Maggiora, Marina, Muzio, Giuliana, Trombetta, Antonella, Cotogni, Paolo, Canuto, Rosa A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute respiratory distress syndrome Arachidonic Acid - administration & dosage Bronchoalveolar Lavage Fluid - chemistry Cell interaction Cyclooxygenase 2 - biosynthesis Dinoprostone - biosynthesis Docosahexaenoic Acids - administration & dosage Fatty acids Fatty Acids, Omega-3 - administration & dosage Fatty Acids, Omega-3 - metabolism Fatty Acids, Omega-6 - administration & dosage Fatty Acids, Omega-6 - metabolism Fish oils Gene Expression Regulation - drug effects Health aspects Humans Inflammation - diet therapy Inflammation - genetics Inflammation - metabolism Inflammation Mediators - chemistry Inflammation Mediators - pharmacology Interleukin-10 - biosynthesis Mortality NF-kappa B - biosynthesis Observations Omega-3 fatty acids Physiological aspects PPAR gamma - biosynthesis Pulmonary Alveoli - chemistry Pulmonary Alveoli - metabolism Respiratory distress syndrome Respiratory Distress Syndrome - diet therapy Respiratory Distress Syndrome - genetics Respiratory Distress Syndrome - metabolism Studies
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!