MALDI Mass Spectrometric Imaging of Lipids in Rat Brain Injury Models

Matrix-assisted laser desorption ionization/ionization imaging mass spectrometry (MALDI IMS) with a time-of-flight analyzer was used to characterize the distribution of lipid molecular species in the brain of rats in two injury models. Ischemia/reperfusion injury of the rat brain after bilateral occ...

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Veröffentlicht in:	Journal of the American Society for Mass Spectrometry 2011-06, Vol.22 (6), p.1014-1021, Article s13361-011-0122-z
Hauptverfasser:	Hankin, Joseph A., Farias, Santiago E., Barkley, Robert M., Heidenreich, Kim, Frey, Lauren C., Hamazaki, Kei, Kim, Hee-Yong, Murphy, Robert C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abundance Analytical Chemistry Animals Apoptosis Bioinformatics Biological and medical sciences Biotechnology Brain Brain Injuries - metabolism CA1 Region, Hippocampal - chemistry CA1 Region, Hippocampal - metabolism Chemistry Chemistry and Materials Science Desorption Disease Models, Animal Edema Focus: MALDI-TOF and Biological MS: Research Article Head injuries Histocytochemistry Investigative techniques, diagnostic techniques (general aspects) Ionization Ions Ischemia Lipids Male Mass spectrometry Medical sciences Miscellaneous. Technology Molecular Imaging Occlusion Organic Chemistry Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Phospholipids Phospholipids - analysis Phospholipids - chemistry Phospholipids - metabolism Proteomics Rats Rats, Sprague-Dawley Reperfusion Injury - metabolism Sodium Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods Traumatic brain injury
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