Use of tilapia piscidin 3 (TP3) to protect against MRSA infection in mice with skin injuries

Antimicrobial peptides (AMPs), represent promising agents for new therapeutic approaches of infected wound treatment, on account of their antimicrobial and wound closure activities, and low potential for inducing resistance. However, therapeutic applications of these AMPs are limited by their toxici...

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Veröffentlicht in:	Oncotarget 2015-05, Vol.6 (15), p.12955-12969
Hauptverfasser:	Huang, Han-Ning, Chan, Yi-Lin, Hui, Cho-Fat, Wu, Jen-Leih, Wu, Chang-Jer, Chen, Jyh-Yih
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Infective Agents - pharmacology Bacteremia - drug therapy Bacteremia - immunology Bacteremia - microbiology Bacteremia - prevention & control Cricetinae Drug Synergism Female Methicillin-Resistant Staphylococcus aureus - drug effects Mice Mice, Inbred BALB C Peptide Fragments - pharmacology Research Paper: Pathology Skin - injuries Skin - microbiology Staphylococcal Infections - drug therapy Staphylococcal Infections - immunology Staphylococcal Infections - prevention & control Staphylococcal Skin Infections - drug therapy Staphylococcal Skin Infections - immunology Staphylococcal Skin Infections - prevention & control Thymopoietins - pharmacology Wound Healing - drug effects Wound Healing - immunology Wound Infection - drug therapy Wound Infection - immunology Wound Infection - microbiology Wound Infection - prevention & control
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