The Evolving Role of Chemical Synthesis in Antibacterial Drug Discovery

The discovery and implementation of antibiotics in the early twentieth century transformed human health and wellbeing. Chemical synthesis enabled the development of the first antibacterial substances, organoarsenicals and sulfa drugs, but these were soon outshone by a host of more powerful and vastl...

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Veröffentlicht in:	Angewandte Chemie International Edition 2014-08, Vol.53 (34), p.8840-8869
Hauptverfasser:	Wright, Peter M., Seiple, Ian B., Myers, Andrew G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemical synthesis Anti-Bacterial Agents - pharmacology Antibiotics Antiinfectives and antibacterials Bacteria Chemical synthesis Chemists Drug Discovery Drug Resistance, Bacterial Drugs Economic factors Evolution Pharmaceutical industry semisynthesis Synthesis Tetracyclines
Online-Zugang:	Volltext
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