Shigella IpaB and IpaD displayed on L. lactis bacterium‐like particles induce protective immunity in adult and infant mice

Shigella spp. are among the enteric pathogens with the highest attributable incidence of moderate‐to‐severe diarrhea in children under 5 years of age living in endemic areas. There are no vaccines available to prevent this disease. In this work, we investigated a new Shigella vaccine concept consist...

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Veröffentlicht in:Immunology and cell biology 2015-08, Vol.93 (7), p.641-652
Hauptverfasser: Heine, Shannon J, Franco‐Mahecha, Olga L, Chen, Xiaotong, Choudhari, Shyamal, Blackwelder, William C, Roosmalen, Maarten L, Leenhouts, Kees, Picking, Wendy L, Pasetti, Marcela F
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Sprache:eng
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