Discovery of an Unconventional Centromere in Budding Yeast Redefines Evolution of Point Centromeres

Centromeres are the chromosomal regions promoting kinetochore assembly for chromosome segregation. In many eukaryotes, the centromere consists of up to mega base pairs of DNA. On such “regional centromeres,” kinetochore assembly is mainly defined by epigenetic regulation [1]. By contrast, a clade of...

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Veröffentlicht in:	Current biology 2015-08, Vol.25 (15), p.2026-2033
Hauptverfasser:	Kobayashi, Norihiko, Suzuki, Yutaka, Schoenfeld, Lori W., Müller, Carolin A., Nieduszynski, Conrad, Wolfe, Kenneth H., Tanaka, Tomoyuki U.
Format:	Artikel
Sprache:	eng
Schlagworte:	Centromere - genetics Centromere - metabolism DNA, Fungal - genetics DNA, Fungal - metabolism Evolution, Molecular Saccharomyces cerevisiae Saccharomycetaceae Saccharomycetales - genetics Saccharomycetales - metabolism
Online-Zugang:	Volltext
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