A genetic and structural analysis of the yeast Vps15 protein kinase: evidence for a direct role of Vps15p in vacuolar protein delivery

The yeast VPS15 gene encodes a novel protein kinase homolog that is required for the sorting of soluble hydrolases to the yeast vacuole. In this study, we extend our previous mutational analysis of the VPS15 gene and show that alterations of specific Gps15p residues, that are highly conserved among...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The EMBO journal 1991-12, Vol.10 (13), p.4049-4060
Hauptverfasser:	Herman, P.K., Stack, J.H., Emr, S.D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Classical genetics, quantitative genetics, hybrids Fundamental and applied biological sciences. Psychology Fungal Proteins - metabolism genes Genes, Fungal Genetics of eukaryotes. Biological and molecular evolution Hydrolases - metabolism lysosomes Mutagenesis, Site-Directed Mutation Myristic Acid Myristic Acids - chemistry Phosphorylation Plasmids Precipitin Tests Protein Kinases - genetics Protein Kinases - metabolism proteins Saccharomyces Saccharomyces cerevisiae - enzymology Saccharomyces cerevisiae - genetics Temperature Thallophyta, bryophyta vacuoles Vacuoles - enzymology Vegetals
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!