Mucosal transcriptomics implicates under expression of BRINP3 in the pathogenesis of ulcerative colitis

Mucosal abnormalities are potentially important in the primary pathogenesis of ulcerative colitis (UC). We investigated the mucosal transcriptomic expression profiles of biopsies from patients with UC and healthy controls, taken from macroscopically noninflamed tissue from the terminal ileum and 3 c...

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Veröffentlicht in:	Inflammatory bowel diseases 2014-10, Vol.20 (10), p.1802-1812
Hauptverfasser:	Smith, Philip J, Levine, Adam P, Dunne, Jenny, Guilhamon, Paul, Turmaine, Mark, Sewell, Gavin W, OʼShea, Nuala R, Vega, Roser, Paterson, Jennifer C, Oukrif, Dahmane, Beck, Stephan, Bloom, Stuart L, Novelli, Marco, Rodriguez-Justo, Manuel, Smith, Andrew M, Segal, Anthony W
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Biomarkers - metabolism Blotting, Western Case-Control Studies Colitis, Ulcerative - genetics Colitis, Ulcerative - pathology Crohn Disease - genetics Crohn Disease - pathology DNA-Binding Proteins - genetics Female Follow-Up Studies Gene Expression Profiling Humans Immunoenzyme Techniques Intestinal Mucosa - metabolism Intestinal Mucosa - pathology Male Middle Aged Oligonucleotide Array Sequence Analysis Original Basic Science Prognosis Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Young Adult
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