The developmental origins of the mammalian ovarian reserve

The adult mammalian ovary is devoid of definitive germline stem cells. As such, female reproductive senescence largely results from the depletion of a finite ovarian follicle pool that is produced during embryonic development. Remarkably, the crucial nature and regulation of follicle assembly and su...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Development (Cambridge) 2015-08, Vol.142 (15), p.2554-2563
Hauptverfasser:	Grive, Kathryn J, Freiman, Richard N
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animals Female Germ Cells - growth & development Humans Mammals - embryology Meiosis - physiology Models, Biological Oocytes - cytology Ovarian Follicle - embryology Ovarian Reserve - physiology Review Signal Transduction - genetics Signal Transduction - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!