Sex Effects in Cocaine-Using Methadone Patients Randomized to Contingency Management Interventions
Contingency management (CM) is an effective treatment for promoting cocaine abstinence in patients receiving methadone maintenance. However, few studies have examined the effect of sex on treatment outcomes in this population. This study evaluated the impact of sex on longest duration of abstinence...
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| Veröffentlicht in: | Experimental and clinical psychopharmacology 2015-08, Vol.23 (4), p.284-290 |
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| creator | Burch, Ashley E Rash, Carla J Petry, Nancy M |
| description | Contingency management (CM) is an effective treatment for promoting cocaine abstinence in patients receiving methadone maintenance. However, few studies have examined the effect of sex on treatment outcomes in this population. This study evaluated the impact of sex on longest duration of abstinence (LDA) and percent negative urine samples in 323 cocaine-using methadone patients from 4 randomized clinical trials comparing CM to standard methadone care. Overall, women had better treatment outcomes compared with men, demonstrated by an increase in both LDA and percentages of negative samples. Patients receiving CM also had significantly higher LDA and percentages of negative samples compared to patients receiving standard care, but sex by treatment condition effects were not significant. These data suggest that cocaine-using methadone patients who are women have better substance use outcomes than men in interventions that regularly monitor cocaine use, and CM is equally efficacious regardless of sex. |
| doi_str_mv | 10.1037/pha0000034 |
| format | Article |
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However, few studies have examined the effect of sex on treatment outcomes in this population. This study evaluated the impact of sex on longest duration of abstinence (LDA) and percent negative urine samples in 323 cocaine-using methadone patients from 4 randomized clinical trials comparing CM to standard methadone care. Overall, women had better treatment outcomes compared with men, demonstrated by an increase in both LDA and percentages of negative samples. Patients receiving CM also had significantly higher LDA and percentages of negative samples compared to patients receiving standard care, but sex by treatment condition effects were not significant. 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These data suggest that cocaine-using methadone patients who are women have better substance use outcomes than men in interventions that regularly monitor cocaine use, and CM is equally efficacious regardless of sex.</description><subject>Adult</subject><subject>Analgesics, Opioid - therapeutic use</subject><subject>Analgesics, Opioid - urine</subject><subject>Analysis of Variance</subject><subject>Behavior Therapy - methods</subject><subject>Chi-Square Distribution</subject><subject>Cocaine</subject><subject>Cocaine-Related Disorders - therapy</subject><subject>Cocaine-Related Disorders - urine</subject><subject>Contingency Management</subject><subject>Drug Abstinence</subject><subject>Female</subject><subject>Human</subject><subject>Human Sex Differences</subject><subject>Humans</subject><subject>Male</subject><subject>Methadone - therapeutic use</subject><subject>Methadone - urine</subject><subject>Methadone Maintenance</subject><subject>Middle Aged</subject><subject>Multicenter Studies as Topic</subject><subject>Randomized Controlled Trials as Topic</subject><subject>Sex Characteristics</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><subject>Treatment Outcomes</subject><issn>1064-1297</issn><issn>1936-2293</issn><isbn>1433821648</isbn><isbn>9781433821646</isbn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkUtv1DAUhS0eou3Ahh-AIrFBoIBfsZ0NEhoVqNQKBHRtOc7NjKvETm2nYvj1eJhSHt74SufTuefqIPSU4NcEM_lm3hq8f4zfQ8ekZaKmtGX30QnhjClKBFcPioAFrwlt5RE6SekK46K29BE6ooIyyag4Rt1X-F6dDgPYnCrnq3WwxnmoL5Pzm-oC8tb0wUP12WQHvjBfjO_D5H5AX-VQcJ8LCN7uqgvjzQamQlVnPkO8KZMLPj1GDwczJnhy-6_Q5fvTb-uP9fmnD2frd-e14ZzmugEhSm7RQCeHoVOMd0q1RHSAuRyIYMpiCkPPKSGSYtG0pmM9N6rvle3KvEJvD77z0k3Q27I-mlHP0U0m7nQwTv-reLfVm3CjeUMbWRas0ItbgxiuF0hZTy5ZGEfjISxJE4mJaqlirKDP_0OvwhJ9Oe8XxSWTfG_48kDZGFKKMNyFIVjve9R_eizws7_j36G_uyrAqwNgZqPntLMmZmdHSHaJsZy0N9OUaa6p4uwna9qm9g</recordid><startdate>201508</startdate><enddate>201508</enddate><creator>Burch, Ashley E</creator><creator>Rash, Carla J</creator><creator>Petry, Nancy M</creator><general>American Psychological Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7RZ</scope><scope>PSYQQ</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201508</creationdate><title>Sex Effects in Cocaine-Using Methadone Patients Randomized to Contingency Management Interventions</title><author>Burch, Ashley E ; Rash, Carla J ; Petry, Nancy M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a442t-5e6616465eb7ffb834b88916be047f1638c02efd4211720659ab3d4a8dd8cbab3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Analgesics, Opioid - therapeutic use</topic><topic>Analgesics, Opioid - urine</topic><topic>Analysis of Variance</topic><topic>Behavior Therapy - methods</topic><topic>Chi-Square Distribution</topic><topic>Cocaine</topic><topic>Cocaine-Related Disorders - therapy</topic><topic>Cocaine-Related Disorders - urine</topic><topic>Contingency Management</topic><topic>Drug Abstinence</topic><topic>Female</topic><topic>Human</topic><topic>Human Sex Differences</topic><topic>Humans</topic><topic>Male</topic><topic>Methadone - therapeutic use</topic><topic>Methadone - urine</topic><topic>Methadone Maintenance</topic><topic>Middle Aged</topic><topic>Multicenter Studies as Topic</topic><topic>Randomized Controlled Trials as Topic</topic><topic>Sex Characteristics</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><topic>Treatment Outcomes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Burch, Ashley E</creatorcontrib><creatorcontrib>Rash, Carla J</creatorcontrib><creatorcontrib>Petry, Nancy M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PsycArticles (via ProQuest)</collection><collection>ProQuest One Psychology</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Experimental and clinical psychopharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Burch, Ashley E</au><au>Rash, Carla J</au><au>Petry, Nancy M</au><au>Reynolds, Brady</au><au>Evans, Suzette M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sex Effects in Cocaine-Using Methadone Patients Randomized to Contingency Management Interventions</atitle><jtitle>Experimental and clinical psychopharmacology</jtitle><addtitle>Exp Clin Psychopharmacol</addtitle><date>2015-08</date><risdate>2015</risdate><volume>23</volume><issue>4</issue><spage>284</spage><epage>290</epage><pages>284-290</pages><issn>1064-1297</issn><eissn>1936-2293</eissn><isbn>1433821648</isbn><isbn>9781433821646</isbn><abstract>Contingency management (CM) is an effective treatment for promoting cocaine abstinence in patients receiving methadone maintenance. 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| subjects | Adult Analgesics, Opioid - therapeutic use Analgesics, Opioid - urine Analysis of Variance Behavior Therapy - methods Chi-Square Distribution Cocaine Cocaine-Related Disorders - therapy Cocaine-Related Disorders - urine Contingency Management Drug Abstinence Female Human Human Sex Differences Humans Male Methadone - therapeutic use Methadone - urine Methadone Maintenance Middle Aged Multicenter Studies as Topic Randomized Controlled Trials as Topic Sex Characteristics Time Factors Treatment Outcome Treatment Outcomes |
| title | Sex Effects in Cocaine-Using Methadone Patients Randomized to Contingency Management Interventions |
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