Plasmodium falciparum full life cycle and Plasmodium ovale liver stages in humanized mice

Experimental studies of Plasmodium parasites that infect humans are restricted by their host specificity. Humanized mice offer a means to overcome this and further provide the opportunity to observe the parasites in vivo . Here we improve on previous protocols to achieve efficient double engraftment...

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Veröffentlicht in:	Nature communications 2015-07, Vol.6 (1), p.7690-7690, Article 7690
Hauptverfasser:	Soulard, Valérie, Bosson-Vanga, Henriette, Lorthiois, Audrey, Roucher, Clémentine, Franetich, Jean- François, Zanghi, Gigliola, Bordessoulles, Mallaury, Tefit, Maurel, Thellier, Marc, Morosan, Serban, Le Naour, Gilles, Capron, Frédérique, Suemizu, Hiroshi, Snounou, Georges, Moreno-Sabater, Alicia, Mazier, Dominique
Format:	Artikel
Sprache:	eng
Schlagworte:	13 14 631/1647/767/1424 631/250/255/1715 631/326/417/1716 631/326/417/2546 64 Animals Biochemistry, Molecular Biology Disease Models, Animal Erythrocyte Transfusion Female Hepatocytes - transplantation Humanities and Social Sciences Humans Life Cycle Stages Life Sciences Liver - parasitology Malaria - parasitology Male Mice, Transgenic multidisciplinary Plasmodium falciparum - growth & development Plasmodium ovale - growth & development Science Science (multidisciplinary) Sporozoites - physiology
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