Human Urine-Derived Renal Progenitors for Personalized Modeling of Genetic Kidney Disorders

The critical role of genetic and epigenetic factors in the pathogenesis of kidney disorders is gradually becoming clear, and the need for disease models that recapitulate human kidney disorders in a personalized manner is paramount. In this study, we describe a method to select and amplify renal pro...

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Veröffentlicht in:	Journal of the American Society of Nephrology 2015-08, Vol.26 (8), p.1961-1974
Hauptverfasser:	Lazzeri, Elena, Ronconi, Elisa, Angelotti, Maria Lucia, Peired, Anna, Mazzinghi, Benedetta, Becherucci, Francesca, Conti, Sara, Sansavini, Giulia, Sisti, Alessandro, Ravaglia, Fiammetta, Lombardi, Duccio, Provenzano, Aldesia, Manonelles, Anna, Cruzado, Josep M, Giglio, Sabrina, Roperto, Rosa Maria, Materassi, Marco, Lasagni, Laura, Romagnani, Paola
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Animals Basic Research Case-Control Studies Cell Culture Techniques Child Child, Preschool Female Humans Infant Kidney - cytology Kidney Diseases - congenital Male Mice, Inbred BALB C Mice, SCID Mice, Transgenic Stem Cells - cytology Urine - cytology
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