The Ecdysone Receptor Coactivator Taiman Links Yorkie to Transcriptional Control of Germline Stem Cell Factors in Somatic Tissue

The Hippo pathway is a conserved signaling cascade that modulates tissue growth. Although its core elements are well defined, factors modulating Hippo transcriptional outputs remain elusive. Here we show that components of the steroid-responsive ecdysone (Ec) pathway modulate Hippo transcriptional e...

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Veröffentlicht in:	Developmental cell 2015-07, Vol.34 (2), p.168-180
Hauptverfasser:	Zhang, Can, Robinson, Brian S., Xu, Wenjian, Yang, Liu, Yao, Bing, Zhao, Heya, Byun, Phil K., Jin, Peng, Veraksa, Alexey, Moberg, Kenneth H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Argonaute Proteins - biosynthesis Argonaute Proteins - genetics Cells, Cultured Drosophila melanogaster Drosophila Proteins - biosynthesis Drosophila Proteins - genetics Drosophila Proteins - metabolism Epithelium - growth & development Gene Expression Regulation, Developmental Intracellular Signaling Peptides and Proteins - metabolism Nuclear Proteins - genetics Nuclear Proteins - metabolism Protein-Serine-Threonine Kinases - metabolism Receptors, Steroid - metabolism RNA Interference RNA, Messenger - biosynthesis RNA, Small Interfering RNA-Binding Proteins - biosynthesis RNA-Binding Proteins - genetics Stem Cell Factor Trans-Activators - genetics Trans-Activators - metabolism Transcription Factors - genetics Transcription Factors - metabolism Transcription, Genetic Wings, Animal - embryology
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