An RNA conformational change between the two chemical steps of group II self‐splicing

As for nuclear pre‐mRNA introns, the splicing pathway of group II self‐splicing introns proceeds by two successive transesterifications involving substrates with different chemical configurations. These two reactions have been proposed to be catalysed by two active sites, or alternatively by a singl...

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Veröffentlicht in:	The EMBO journal 1996-07, Vol.15 (13), p.3466-3476
Hauptverfasser:	Chanfreau, G., Jacquier, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Catalysis Introns Molecular Sequence Data Nucleic Acid Conformation RNA - chemistry RNA Splicing
Online-Zugang:	Volltext
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