Cerebral Malaria Complicated by Blindness, Deafness and Extrapyramidal Tract Manifestation

Cerebral Malaria Complicated by Blindness, Deafness and Extrapyramidal Tract Manifestation

Cerebral malaria is a severe manifestation of a parasitic infection caused by Plasmodium falciparum. The sequelae of this disease such as blindness, deafness, loss of motor function could be emotionally traumatic and physically disabling. We, therefore, present this case of an 8-year-old boy who pre...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Annals of medical and health sciences research 2015-07, Vol.5 (4), p.321-322
Hauptverfasser: Manyike, P C, Okike, C, Onyire, N B, Chinawa, J M, Austin-Abu, J U
Format: Artikel
Sprache:eng
Schlagworte:
Blindness
Care and treatment
Case studies
Complications and side effects
Development and progression
Hearing loss
Malaria
Short Communication
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 322
container_issue 4
container_start_page 321
container_title Annals of medical and health sciences research
container_volume 5
creator Manyike, P C
Okike, C
Onyire, N B
Chinawa, J M
Austin-Abu, J U
description Cerebral malaria is a severe manifestation of a parasitic infection caused by Plasmodium falciparum. The sequelae of this disease such as blindness, deafness, loss of motor function could be emotionally traumatic and physically disabling. We, therefore, present this case of an 8-year-old boy who presented with high-grade intermittent fever associated with multiple convulsions and prolonged coma. He regained consciousness after 12 days of treatment with intravenous quinine but was found to have blindness, sensory-neural deafness and extrapyramidal sign. This extrapyramidal sign regressed following treatment with chlorpromazine. He also regained his sight and auditory function before he was discharged though not completely. This report is aimed at emphasizing these rare complications of cerebral malaria as well as reminding clinicians working in malaria endemic areas of the world on the need for early diagnosis and prompt treatment.
doi_str_mv 10.4103/2141-9248.160183
format Article
fullrecord <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4512129</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A421729166</galeid><sourcerecordid>A421729166</sourcerecordid><originalsourceid>FETCH-LOGICAL-c346t-4cc24b9a8b1699941cfe9c3f8caee3c46cb25e632689dc09908979dc12c18ae03</originalsourceid><addsrcrecordid>eNptkc1v1DAQxS1ERavSOycUiQsHdvE4jhNfkMpSPqRWvbQXLtbEmRQjx17sLGL_exxtW1EJ--DRzO89jfUYewV8LYHX7wVIWGkhuzUoDl39jJ0I0balxZvnpX4YH7OznH_yclQjuYAX7FgoIXQrmhP2fUOJ-oS-ukKPyWG1idPWO4szDVW_rz56F4ZAOb-rPhGOS1VhGKqLP3PC7T7h5Iaivklo5-IR3Eh5xtnF8JIdjegznd2_p-z288XN5uvq8vrLt8355crWUs0raa2QvcauB6W1lmBH0rYeO4tEtZXK9qIhVQvV6cFyrXmn21KBsNAh8fqUfTj4bnf9RIOlUDbzZpvchGlvIjrzdBLcD3MXfxvZgAChi8Hbe4MUf-3K-mZy2ZL3GCjusoGWL5gGVdA3B_QOPRkXxlgc7YKbcymgFQVaqPV_qHIHmpyNgUZX-k8E_CCwKeacaHzcHrhZwjZLmmZJ0xzCLpLX__76UfAQbf0XeJ6kEg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1701293916</pqid></control><display><type>article</type><title>Cerebral Malaria Complicated by Blindness, Deafness and Extrapyramidal Tract Manifestation</title><source>PubMed Central Open Access</source><source>African Journals Online (Open Access)</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Manyike, P C ; Okike, C ; Onyire, N B ; Chinawa, J M ; Austin-Abu, J U</creator><creatorcontrib>Manyike, P C ; Okike, C ; Onyire, N B ; Chinawa, J M ; Austin-Abu, J U</creatorcontrib><description>Cerebral malaria is a severe manifestation of a parasitic infection caused by Plasmodium falciparum. The sequelae of this disease such as blindness, deafness, loss of motor function could be emotionally traumatic and physically disabling. We, therefore, present this case of an 8-year-old boy who presented with high-grade intermittent fever associated with multiple convulsions and prolonged coma. He regained consciousness after 12 days of treatment with intravenous quinine but was found to have blindness, sensory-neural deafness and extrapyramidal sign. This extrapyramidal sign regressed following treatment with chlorpromazine. He also regained his sight and auditory function before he was discharged though not completely. This report is aimed at emphasizing these rare complications of cerebral malaria as well as reminding clinicians working in malaria endemic areas of the world on the need for early diagnosis and prompt treatment.</description><identifier>ISSN: 2141-9248</identifier><identifier>EISSN: 2277-9205</identifier><identifier>DOI: 10.4103/2141-9248.160183</identifier><identifier>PMID: 26229725</identifier><language>eng</language><publisher>India: Medknow Publications and Media Pvt. Ltd</publisher><subject>Blindness ; Care and treatment ; Case studies ; Complications and side effects ; Development and progression ; Hearing loss ; Malaria ; Short Communication</subject><ispartof>Annals of medical and health sciences research, 2015-07, Vol.5 (4), p.321-322</ispartof><rights>COPYRIGHT 2015 Medknow Publications and Media Pvt. Ltd.</rights><rights>Copyright: © Annals of Medical and Health Sciences Research 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512129/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512129/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26229725$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Manyike, P C</creatorcontrib><creatorcontrib>Okike, C</creatorcontrib><creatorcontrib>Onyire, N B</creatorcontrib><creatorcontrib>Chinawa, J M</creatorcontrib><creatorcontrib>Austin-Abu, J U</creatorcontrib><title>Cerebral Malaria Complicated by Blindness, Deafness and Extrapyramidal Tract Manifestation</title><title>Annals of medical and health sciences research</title><addtitle>Ann Med Health Sci Res</addtitle><description>Cerebral malaria is a severe manifestation of a parasitic infection caused by Plasmodium falciparum. The sequelae of this disease such as blindness, deafness, loss of motor function could be emotionally traumatic and physically disabling. We, therefore, present this case of an 8-year-old boy who presented with high-grade intermittent fever associated with multiple convulsions and prolonged coma. He regained consciousness after 12 days of treatment with intravenous quinine but was found to have blindness, sensory-neural deafness and extrapyramidal sign. This extrapyramidal sign regressed following treatment with chlorpromazine. He also regained his sight and auditory function before he was discharged though not completely. This report is aimed at emphasizing these rare complications of cerebral malaria as well as reminding clinicians working in malaria endemic areas of the world on the need for early diagnosis and prompt treatment.</description><subject>Blindness</subject><subject>Care and treatment</subject><subject>Case studies</subject><subject>Complications and side effects</subject><subject>Development and progression</subject><subject>Hearing loss</subject><subject>Malaria</subject><subject>Short Communication</subject><issn>2141-9248</issn><issn>2277-9205</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNptkc1v1DAQxS1ERavSOycUiQsHdvE4jhNfkMpSPqRWvbQXLtbEmRQjx17sLGL_exxtW1EJ--DRzO89jfUYewV8LYHX7wVIWGkhuzUoDl39jJ0I0balxZvnpX4YH7OznH_yclQjuYAX7FgoIXQrmhP2fUOJ-oS-ukKPyWG1idPWO4szDVW_rz56F4ZAOb-rPhGOS1VhGKqLP3PC7T7h5Iaivklo5-IR3Eh5xtnF8JIdjegznd2_p-z288XN5uvq8vrLt8355crWUs0raa2QvcauB6W1lmBH0rYeO4tEtZXK9qIhVQvV6cFyrXmn21KBsNAh8fqUfTj4bnf9RIOlUDbzZpvchGlvIjrzdBLcD3MXfxvZgAChi8Hbe4MUf-3K-mZy2ZL3GCjusoGWL5gGVdA3B_QOPRkXxlgc7YKbcymgFQVaqPV_qHIHmpyNgUZX-k8E_CCwKeacaHzcHrhZwjZLmmZJ0xzCLpLX__76UfAQbf0XeJ6kEg</recordid><startdate>20150701</startdate><enddate>20150701</enddate><creator>Manyike, P C</creator><creator>Okike, C</creator><creator>Onyire, N B</creator><creator>Chinawa, J M</creator><creator>Austin-Abu, J U</creator><general>Medknow Publications and Media Pvt. Ltd</general><general>Medknow Publications &amp; Media Pvt Ltd</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20150701</creationdate><title>Cerebral Malaria Complicated by Blindness, Deafness and Extrapyramidal Tract Manifestation</title><author>Manyike, P C ; Okike, C ; Onyire, N B ; Chinawa, J M ; Austin-Abu, J U</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c346t-4cc24b9a8b1699941cfe9c3f8caee3c46cb25e632689dc09908979dc12c18ae03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Blindness</topic><topic>Care and treatment</topic><topic>Case studies</topic><topic>Complications and side effects</topic><topic>Development and progression</topic><topic>Hearing loss</topic><topic>Malaria</topic><topic>Short Communication</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Manyike, P C</creatorcontrib><creatorcontrib>Okike, C</creatorcontrib><creatorcontrib>Onyire, N B</creatorcontrib><creatorcontrib>Chinawa, J M</creatorcontrib><creatorcontrib>Austin-Abu, J U</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Annals of medical and health sciences research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Manyike, P C</au><au>Okike, C</au><au>Onyire, N B</au><au>Chinawa, J M</au><au>Austin-Abu, J U</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cerebral Malaria Complicated by Blindness, Deafness and Extrapyramidal Tract Manifestation</atitle><jtitle>Annals of medical and health sciences research</jtitle><addtitle>Ann Med Health Sci Res</addtitle><date>2015-07-01</date><risdate>2015</risdate><volume>5</volume><issue>4</issue><spage>321</spage><epage>322</epage><pages>321-322</pages><issn>2141-9248</issn><eissn>2277-9205</eissn><abstract>Cerebral malaria is a severe manifestation of a parasitic infection caused by Plasmodium falciparum. The sequelae of this disease such as blindness, deafness, loss of motor function could be emotionally traumatic and physically disabling. We, therefore, present this case of an 8-year-old boy who presented with high-grade intermittent fever associated with multiple convulsions and prolonged coma. He regained consciousness after 12 days of treatment with intravenous quinine but was found to have blindness, sensory-neural deafness and extrapyramidal sign. This extrapyramidal sign regressed following treatment with chlorpromazine. He also regained his sight and auditory function before he was discharged though not completely. This report is aimed at emphasizing these rare complications of cerebral malaria as well as reminding clinicians working in malaria endemic areas of the world on the need for early diagnosis and prompt treatment.</abstract><cop>India</cop><pub>Medknow Publications and Media Pvt. Ltd</pub><pmid>26229725</pmid><doi>10.4103/2141-9248.160183</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2141-9248
ispartof Annals of medical and health sciences research, 2015-07, Vol.5 (4), p.321-322
issn 2141-9248
2277-9205
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4512129
source PubMed Central Open Access; African Journals Online (Open Access); EZB-FREE-00999 freely available EZB journals; PubMed Central
subjects Blindness
Care and treatment
Case studies
Complications and side effects
Development and progression
Hearing loss
Malaria
Short Communication
title Cerebral Malaria Complicated by Blindness, Deafness and Extrapyramidal Tract Manifestation
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T00%3A20%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Cerebral%20Malaria%20Complicated%20by%20Blindness,%20Deafness%20and%20Extrapyramidal%20Tract%20Manifestation&rft.jtitle=Annals%20of%20medical%20and%20health%20sciences%20research&rft.au=Manyike,%20P%20C&rft.date=2015-07-01&rft.volume=5&rft.issue=4&rft.spage=321&rft.epage=322&rft.pages=321-322&rft.issn=2141-9248&rft.eissn=2277-9205&rft_id=info:doi/10.4103/2141-9248.160183&rft_dat=%3Cgale_pubme%3EA421729166%3C/gale_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1701293916&rft_id=info:pmid/26229725&rft_galeid=A421729166&rfr_iscdi=true