Biocompatible D-Penicillamine Conjugated Au Nanoparticles: Targeting Intracellular Free Copper Ions for Detoxification

High thiophillicicity of the Au-nanoparticle (Au NP) surface leads to covalent attachment of D-penicillamine molecules to Au NPs to form biocompatible D-penicillamine conjugated Au NPs. The latter are highly water-dispersible, exhibit no cytotoxicity, and can readily penetrate the cell membrane to t...

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Veröffentlicht in:	Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2015-07, Vol.3 (27), p.5553-5559
Hauptverfasser:	Kandanapitiye, Murthi S, Gunathilake, Chamila, Jaroniec, Mietek, Huang, Songping D
Format:	Artikel
Sprache:	eng
Schlagworte:	Attachment Biocompatibility Biology Copper Covalence Disorders Effectiveness Nanoparticles
Online-Zugang:	Volltext
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