IGF1 Promotes Adipogenesis by a Lineage Bias of Endogenous Adipose Stem/Progenitor Cells

Adipogenesis is essential for soft tissue reconstruction following trauma or tumor resection. We demonstrate that CD31−/34+/146− cells, a subpopulation of the stromal vascular fraction (SVF) of human adipose tissue, were robustly adipogenic. Insulin growth factor‐1 (IGF1) promoted a lineage bias tow...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2015-08, Vol.33 (8), p.2483-2495
Hauptverfasser:	Hu, Li, Yang, Guodong, Hägg, Daniel, Sun, Guoming, Ahn, Jeffrey M., Jiang, Nan, Ricupero, Christopher L., Wu, June, Rodhe, Christine Hsu, Ascherman, Jeffrey A., Chen, Lili, Mao, Jeremy J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - metabolism Adipogenesis Adipose Adipose tissue Adult Animals Antigens, Differentiation - metabolism Axin2 Bias CD146 Cell Differentiation Female Humans Insulin growth factor‐1 Insulin-Like Growth Factor I - metabolism Mesenchymal Mice Middle Aged PPARγ Stem cells Stem Cells - metabolism Stromal vascular fraction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!