Human posterior parietal cortex encodes the movement goal in a pro-/anti-reach task
Previous research on reach planning in humans has implicated a frontoparietal network, including the precuneus (PCu), a putative human homolog of the monkey parietal reach region (PRR), and the dorsal premotor cortex (PMd). Using a pro-/anti-reach task, electrophysiological studies in monkeys have d...
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description | Previous research on reach planning in humans has implicated a frontoparietal network, including the precuneus (PCu), a putative human homolog of the monkey parietal reach region (PRR), and the dorsal premotor cortex (PMd). Using a pro-/anti-reach task, electrophysiological studies in monkeys have demonstrated that the movement goal rather than the location of the visual cue is encoded in PRR and PMd. However, if only the effector but not the movement goal is specified (underspecified condition), the PRR and PMd have been shown to represent all potential movement goals. In this functional magnetic resonance imaging study, we investigated whether the human PCu and PMd likewise encode the movement goal, and whether these reach-related areas also engage in situations with underspecified compared with specified movement goals. By using a pro-/anti-reach task, we spatially dissociated the location of the visual cue from the location of the movement goal. In the specified conditions, pro- and anti-reaches activated similar parietal and premotor areas. In the PCu contralateral to the moving arm, we found directionally selective activation fixed to the movement goal. In the underspecified conditions, we observed activation in reach-related areas of the posterior parietal cortex, including PCu. However, the activation was substantially weaker in parietal areas and lacking in PMd. Our results suggest that human PCu encodes the movement goal rather than the location of the visual cue if the movement goal is specified and even engages in situations when only the visual cue but not the movement goal is defined. |
doi_str_mv | 10.1152/jn.01039.2014 |
format | Article |
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Using a pro-/anti-reach task, electrophysiological studies in monkeys have demonstrated that the movement goal rather than the location of the visual cue is encoded in PRR and PMd. However, if only the effector but not the movement goal is specified (underspecified condition), the PRR and PMd have been shown to represent all potential movement goals. In this functional magnetic resonance imaging study, we investigated whether the human PCu and PMd likewise encode the movement goal, and whether these reach-related areas also engage in situations with underspecified compared with specified movement goals. By using a pro-/anti-reach task, we spatially dissociated the location of the visual cue from the location of the movement goal. In the specified conditions, pro- and anti-reaches activated similar parietal and premotor areas. In the PCu contralateral to the moving arm, we found directionally selective activation fixed to the movement goal. In the underspecified conditions, we observed activation in reach-related areas of the posterior parietal cortex, including PCu. However, the activation was substantially weaker in parietal areas and lacking in PMd. Our results suggest that human PCu encodes the movement goal rather than the location of the visual cue if the movement goal is specified and even engages in situations when only the visual cue but not the movement goal is defined.</description><identifier>ISSN: 0022-3077</identifier><identifier>EISSN: 1522-1598</identifier><identifier>DOI: 10.1152/jn.01039.2014</identifier><identifier>PMID: 25904714</identifier><language>eng</language><publisher>United States: American Physiological Society</publisher><subject>Adult ; Arm - physiology ; Brain Mapping ; Control of Movement ; Female ; Goals ; Humans ; Magnetic Resonance Imaging ; Male ; Neuropsychological Tests ; Parietal Lobe - physiology ; Psychomotor Performance - physiology ; Young Adult</subject><ispartof>Journal of neurophysiology, 2015-07, Vol.114 (1), p.170-183</ispartof><rights>Copyright © 2015 the American Physiological Society.</rights><rights>Copyright © 2015 the American Physiological Society 2015 American Physiological Society</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c387t-b7b9b920c8a23e875538ea697d92840a724c8e53e1f250cdab66ec1927ddc893</citedby><cites>FETCH-LOGICAL-c387t-b7b9b920c8a23e875538ea697d92840a724c8e53e1f250cdab66ec1927ddc893</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,3039,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25904714$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gertz, Hanna</creatorcontrib><creatorcontrib>Fiehler, Katja</creatorcontrib><title>Human posterior parietal cortex encodes the movement goal in a pro-/anti-reach task</title><title>Journal of neurophysiology</title><addtitle>J Neurophysiol</addtitle><description>Previous research on reach planning in humans has implicated a frontoparietal network, including the precuneus (PCu), a putative human homolog of the monkey parietal reach region (PRR), and the dorsal premotor cortex (PMd). 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In the underspecified conditions, we observed activation in reach-related areas of the posterior parietal cortex, including PCu. However, the activation was substantially weaker in parietal areas and lacking in PMd. Our results suggest that human PCu encodes the movement goal rather than the location of the visual cue if the movement goal is specified and even engages in situations when only the visual cue but not the movement goal is defined.</description><subject>Adult</subject><subject>Arm - physiology</subject><subject>Brain Mapping</subject><subject>Control of Movement</subject><subject>Female</subject><subject>Goals</subject><subject>Humans</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Neuropsychological Tests</subject><subject>Parietal Lobe - physiology</subject><subject>Psychomotor Performance - physiology</subject><subject>Young Adult</subject><issn>0022-3077</issn><issn>1522-1598</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkUlPwzAQhS0EgrIcuSIfuaSMnTiOL0ioYpOQOMDdcpxpm5LYwXYr-PeErYLTjGY-vXmaR8gpgyljgl-s3BQY5GrKgRU7ZDLOeMaEqnbJBGDsc5DygBzGuAIAKYDvkwMuFBSSFRPydLfujaODjwlD6wMdTGgxmY5aHxK-UXTWNxhpWiLt_QZ7dIku_Ai0jho6BJ9dGJfaLKCxS5pMfDkme3PTRTz5qUfk-eb6eXaXPTze3s-uHjKbVzJltaxVrTjYyvAcKylEXqEplWwUrwowkhe2QpEjm3MBtjF1WaJlisumsZXKj8jlt-ywrnts7GgsmE4Poe1NeNfetPr_xrVLvfAbXQiQSpSjwPmPQPCva4xJ92202HXGoV9HzUpVMjV-V45o9o3a4GMMON-eYaA_c9Arp79y0J85jPzZX29b-vfx-Qe-YISJ</recordid><startdate>20150701</startdate><enddate>20150701</enddate><creator>Gertz, Hanna</creator><creator>Fiehler, Katja</creator><general>American Physiological Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20150701</creationdate><title>Human posterior parietal cortex encodes the movement goal in a pro-/anti-reach task</title><author>Gertz, Hanna ; Fiehler, Katja</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c387t-b7b9b920c8a23e875538ea697d92840a724c8e53e1f250cdab66ec1927ddc893</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Arm - physiology</topic><topic>Brain Mapping</topic><topic>Control of Movement</topic><topic>Female</topic><topic>Goals</topic><topic>Humans</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Neuropsychological Tests</topic><topic>Parietal Lobe - physiology</topic><topic>Psychomotor Performance - physiology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gertz, Hanna</creatorcontrib><creatorcontrib>Fiehler, Katja</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of neurophysiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gertz, Hanna</au><au>Fiehler, Katja</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Human posterior parietal cortex encodes the movement goal in a pro-/anti-reach task</atitle><jtitle>Journal of neurophysiology</jtitle><addtitle>J Neurophysiol</addtitle><date>2015-07-01</date><risdate>2015</risdate><volume>114</volume><issue>1</issue><spage>170</spage><epage>183</epage><pages>170-183</pages><issn>0022-3077</issn><eissn>1522-1598</eissn><abstract>Previous research on reach planning in humans has implicated a frontoparietal network, including the precuneus (PCu), a putative human homolog of the monkey parietal reach region (PRR), and the dorsal premotor cortex (PMd). 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In the underspecified conditions, we observed activation in reach-related areas of the posterior parietal cortex, including PCu. However, the activation was substantially weaker in parietal areas and lacking in PMd. Our results suggest that human PCu encodes the movement goal rather than the location of the visual cue if the movement goal is specified and even engages in situations when only the visual cue but not the movement goal is defined.</abstract><cop>United States</cop><pub>American Physiological Society</pub><pmid>25904714</pmid><doi>10.1152/jn.01039.2014</doi><tpages>14</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Arm - physiology Brain Mapping Control of Movement Female Goals Humans Magnetic Resonance Imaging Male Neuropsychological Tests Parietal Lobe - physiology Psychomotor Performance - physiology Young Adult |
title | Human posterior parietal cortex encodes the movement goal in a pro-/anti-reach task |
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