Genomic modulators of gene expression in human neutrophils

Neutrophils form the most abundant leukocyte subset and are central to many disease processes. Technical challenges in transcriptomic profiling have prohibited genomic approaches to date. Here we map expression quantitative trait loci (eQTL) in peripheral blood CD16+ neutrophils from 101 healthy Eur...

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Veröffentlicht in:	Nature communications 2015-07, Vol.6 (1), p.7545-7545, Article 7545
Hauptverfasser:	Naranbhai, Vivek, Fairfax, Benjamin P., Makino, Seiko, Humburg, Peter, Wong, Daniel, Ng, Esther, Hill, Adrian V. S., Knight, Julian C.
Format:	Artikel
Sprache:	eng
Schlagworte:	38 38/39 38/61 38/77 631/208/729/743 631/250/2502 631/250/2504/223/1699 692/420/2489/144 Adult Allergies Blood Crohn's disease DNA methylation Epigenetics Female Gene expression Gene Expression Regulation - physiology Gene mapping Genetic Variation Genetics Genomes Genomics - methods Genotype Humanities and Social Sciences Humans Infectious diseases Leukocytes Male multidisciplinary Neutrophils Neutrophils - metabolism Quantitative Trait Loci Rheumatoid arthritis Science Science (multidisciplinary)
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