Cell-selective labelling of proteomes in Drosophila melanogaster

The specification and adaptability of cells rely on changes in protein composition. Nonetheless, uncovering proteome dynamics with cell-type-specific resolution remains challenging. Here we introduce a strategy for cell-specific analysis of newly synthesized proteomes by combining targeted expressio...

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Veröffentlicht in:	Nature communications 2015-07, Vol.6 (1), p.7521, Article 7521
Hauptverfasser:	Erdmann, Ines, Marter, Kathrin, Kobler, Oliver, Niehues, Sven, Abele, Julia, Müller, Anke, Bussmann, Julia, Storkebaum, Erik, Ziv, Tamar, Thomas, Ulrich, Dieterich, Daniela C.
Format:	Artikel
Sprache:	eng
Schlagworte:	13 14/19 631/1647/334/1582/715 631/337/475 631/378/2632/1664 631/553/1886 64/24 82 82/58 82/80 Alkynes Amino Acids - chemistry Amino Acids - metabolism Animals Click Chemistry Drosophila melanogaster - genetics Drosophila melanogaster - metabolism Glycine - metabolism Humanities and Social Sciences Methionine - metabolism Methionine-tRNA Ligase - genetics multidisciplinary Mutation Proteome - metabolism Science Science (multidisciplinary) Staining and Labeling - methods
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