Expanding regulatory T cells alleviates chikungunya virus-induced pathology in mice

Chikungunya virus (CHIKV) infection is a re-emerging pandemic human arboviral disease. CD4 T cells were previously shown to contribute to joint inflammation in the course of CHIKV infection in mice. The JES6-1 anti-IL-2 antibody selectively expands mouse regulatory T cells (Tregs) by forming a compl...

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Veröffentlicht in:	Journal of virology 2015-08, Vol.89 (15), p.7893-7904
Hauptverfasser:	Lee, Wendy W L, Teo, Teck-Hui, Her, Zhisheng, Lum, Fok-Moon, Kam, Yiu-Wing, Haase, Doreen, Rénia, Laurent, Rötzschke, Olaf, Ng, Lisa F P
Format:	Artikel
Sprache:	eng
Schlagworte:	Chikungunya virus Pathogenesis and Immunity Spotlight
Online-Zugang:	Volltext
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