Trans-regulation of Syndecan Functions by Hetero-oligomerization

Syndecans, a family of transmembrane heparansulfate proteoglycans, are known to interact through their transmembrane domains to form non-covalently linked homodimers, a process essential for their individual functions. Because all syndecan transmembrane domains are highly conserved and thus might me...

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Veröffentlicht in:	The Journal of biological chemistry 2015-07, Vol.290 (27), p.16943-16953
Hauptverfasser:	Choi, Youngsil, Kwon, Mi-Jung, Lim, Yangmi, Yun, Ji-Hye, Lee, Weontae, Oh, Eok-Soo
Format:	Artikel
Sprache:	eng
Schlagworte:	adhesion Amino Acid Motifs Animals cell migration cell signaling cell surface receptor Dimerization extracellular matrix Fibroblasts - chemistry Fibroblasts - metabolism Glycobiology and Extracellular Matrices membrane oligomerization Protein Binding proteoglycan Rats receptor structure-function syndecan Syndecan-2 - chemistry Syndecan-2 - genetics Syndecan-2 - metabolism Syndecan-4 - chemistry Syndecan-4 - genetics Syndecan-4 - metabolism
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