Mapping dopaminergic deficiencies in the substantia nigra/ventral tegmental area in schizophrenia

Previous work from our laboratory showed deficits in tyrosine hydroxylase protein expression within the substantia nigra/ventral tegmental area (SN/VTA) in schizophrenia. However, little is known about the nature and specific location of these deficits within the SN/VTA. The present study had two ai...

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Veröffentlicht in:	Brain Structure and Function 2016-01, Vol.221 (1), p.185-201
Hauptverfasser:	Rice, Matthew W., Roberts, Rosalinda C., Melendez-Ferro, Miguel, Perez-Costas, Emma
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biomedical and Life Sciences Biomedicine Brain research Cell Biology Cell Count Dopamine Dopamine - metabolism Dopaminergic Neurons - metabolism Dopaminergic Neurons - pathology Female Humans Immunohistochemistry Male Middle Aged Neurology Neuropathology Neuropsychology Neurosciences Original Article Qualitative research Schizophrenia Schizophrenia - metabolism Schizophrenia - pathology Substantia Nigra - metabolism Substantia Nigra - pathology Tyrosine 3-Monooxygenase - metabolism Ventral Tegmental Area - metabolism Ventral Tegmental Area - pathology
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