IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO

The WHO 2007 classification of tumors of the CNS distinguishes between diffuse astrocytoma WHO grade II (A II WHO2007 ) and anaplastic astrocytoma WHO grade III (AA III WHO2007 ). Patients with A II WHO2007 are significantly younger and survive significantly longer than those with AA III WHO2007 . S...

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Veröffentlicht in:	Acta neuropathologica 2015-06, Vol.129 (6), p.867-873
Hauptverfasser:	Reuss, David E., Mamatjan, Yasin, Schrimpf, Daniel, Capper, David, Hovestadt, Volker, Kratz, Annekathrin, Sahm, Felix, Koelsche, Christian, Korshunov, Andrey, Olar, Adriana, Hartmann, Christian, Reijneveld, Jaap C., Wesseling, Pieter, Unterberg, Andreas, Platten, Michael, Wick, Wolfgang, Herold-Mende, Christel, Aldape, Kenneth, von Deimling, Andreas
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age Age Distribution Astrocytoma - classification Astrocytoma - genetics Astrocytoma - mortality Astrocytomas Brain cancer Brain Neoplasms - classification Brain Neoplasms - genetics Brain Neoplasms - mortality Cancer research Chromosomes, Human, Pair 1 Consortia Female Humans Isocitrate Dehydrogenase - genetics Male Medical prognosis Medical research Medicine Medicine & Public Health Middle Aged Mutation Mutation - genetics Neuropathology Neurosciences Original Paper Pathology Research centers Survival Analysis Tumors World Health Organization Young Adult
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